Cyclosporine modified 100-mg, 30-count, (Manufacturer may vary)

Cyclosporine Modified 100 mg for Dogs

Immune Modulating Support for Chronic Conditions

Cyclosporine Modified 100 mg is an immunosuppressant medication specially formulated for dogs to manage chronic autoimmune conditions, particularly atopic dermatitis (allergic skin disease). This oral capsule works by modulating the immune system to reduce inflammatory responses and allergic reactions that cause discomfort in dogs.

Cyclosporine (modified)—a lipophilic is a cyclic polypeptide immunosuppressant. The "modified" form increases its bioavailability, ensuring consistent absorption and therapeutic effectiveness compared to non-modified versions.

It is most commonly prescribed to manage:

• Canine atopic dermatitis (skin allergies)

• Perianal fistulas

• Autoimmune disorders (e.g., pemphigus foliaceus)

• Dry eye syndrome (keratoconjunctivitis sicca – KCS)

What Are the Benefits of Cyclosporine Modified 100 mg for Dogs?

Compared to standard formulations or compounded alternatives, Cyclosporine Modified 100 mg provides enhanced immune modulation with consistent absorption, making it a more reliable solution for chronic skin and autoimmune issues.

• Targets underlying inflammation causing itching, redness, and skin lesions

• Improved absorption for better therapeutic response (Modified form = higher bioavailability)

• Steroid-sparing agent – Reduces need for corticosteroids, minimizing side effects

• Long-term safety profile in managing chronic immune-mediated conditions

• Minimizes flare-ups of allergies and immune-related skin problems

• Vet-recommended for dogs intolerant to steroids or antihistamines

How Should Cyclosporine Modified 100 mg Be Administered? (Dosage and Administration)

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

Typical administration guidelines:

• Given orally once daily, preferably on an empty stomach

• Do not open or crush capsules; administer whole

• Onset of improvement is often visible within 2–3 weeks

• Dosage may be tapered over time as condition improves

What Are the Ingredients in Cyclosporine Modified 100 mg Capsules?

Active Ingredient: Cyclosporine USP – 100 mg per capsule

Inactive Ingredients May Include:

• Ethanol

• Corn oil-mono-di-triglycerides

• Propylene glycol

• Gelatin capsule shell

Note: Specific excipients may vary by manufacturer. Please refer to label or consult with your vet.

How Does Cyclosporine Modified Compare to Other Allergy Medications for Dogs?

When it comes to managing chronic skin allergies, pet owners often ask: Is cyclosporine better than Apoquel or steroids like prednisone?

Here's a quick comparison table for context:

Why Choose Cyclosporine?

• More effective for deep immune-driven skin issues

• Preferred when dogs don’t tolerate steroids or Apoquel

• Safer for long-term use with fewer hormonal side effects

What Results Can You Expect With Cyclosporine Modified?

Most pet parents see visible improvement in their dog’s skin within 2 to 3 weeks, especially in terms of:

• Reduced scratching and licking

• Less redness and skin lesions

• Hair regrowth in previously irritated areas

• Improved comfort and behavior

💡 Tip from real users: Consistency is key. Skipping doses or stopping too early can lead to flare-ups.

Tips for Administering Cyclosporine to Picky Dogs

If your dog is fussy or resists pills, here are user-tested tricks:

• Use pill pockets or wrap in soft cheese or peanut butter

• Administer on empty stomach for better absorption (unless vet advises otherwise)

• Use a pill dispenser or pill gun for accurate delivery

• Try freezing the capsule briefly – it helps reduce the smell and makes it easier to swallow

Are There Any Side Effects of Cyclosporine in Dogs?

Most side effects are mild and transient, especially when compared to corticosteroids.

Common Side Effects:

• Vomiting or soft stool (especially in early treatment phase)

• Loss of appetite

• Lethargy

Less Common But Serious Reactions:

• Gum hyperplasia (overgrowth)

• Hirsutism (excessive hair growth)

• Opportunistic infections (due to immune suppression)

• Neoplasia risk with long-term use (rare – monitor periodically)

If any unusual symptoms occur, contact your veterinarian immediately.

What Warnings or Precautions Should I Know About?

• Not for use in dogs with existing malignancies or hypersensitivity to cyclosporine

• Avoid use in pregnant or lactating dogs unless directed by vet

• Immunosuppression may increase susceptibility to infections

• Regular monitoring of liver and kidney function is advised during long-term treatment

• Do not administer with live vaccines or nephrotoxic drugs

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Note: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Cyclosporine Modified 100 mg FAQs

What is Cyclosporine Modified used for in dogs?

Cyclosporine Modified is used to treat autoimmune and inflammatory conditions in dogs, especially chronic atopic dermatitis and perianal fistulas.

How long can a dog stay on Cyclosporine Modified?

Long-term use is possible under veterinary supervision, with regular monitoring for side effects and adjustments based on symptom control.

Can Cyclosporine be used with other medications?

Yes, but avoid using it with immunosuppressive drugs or nephrotoxic agents unless your vet approves. Drug interactions should be closely monitored.

Does Cyclosporine treat allergies or just symptoms?

It targets immune system overactivity, thereby treating the underlying cause of allergic skin disease, not just the symptoms.

What happens if I miss a dose of Cyclosporine Modified?

Administer the missed dose as soon as you remember. If it’s close to the next scheduled dose, skip the missed one and continue as directed. Never double-dose.

Clinical Research

• Cyclosporine Approval Info: https://www.fda.gov/animal-veterinary/animal-drug-compounding/list-bulk-drug-substances-compounding-office-stock-drugs-use-nonfood-producing-animals
• Cyclosporine Use in Dogs: https://www.msdvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-eye/immunosuppressive-drugs-in-animals
• Understanding Atopic Dermatitis in Dogs: https://www.vet.cornell.edu/departments-centers-and-institutes/riney-canine-health-center/canine-health-information/atopic-dermatitis-atopy